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Genomic function (communication arising)

Rate of evolution and gene dispensability

Nature volume 421, pages 497–498 (2003)Cite this article

Abstract

The relationship between protein dispensability and rate of evolution that we detected in yeast1 has since been confirmed among bacteria2 — as well as in the same data set3,4 that Pal et al. refer to as “new fitness data” and which they re-analyse here using methods that fail to reveal the relationship.

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References

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Author information

Authors and Affiliations

  1. Department of Biological Sciences, Stanford University, Stanford, 94305, California, USA

    Aaron E. Hirsh

  2. Department of Molecular and Cell Biology, University of California, Berkeley, 94720, California, USA

    Hunter B. Fraser

Authors
  1. Aaron E. Hirsh
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  2. Hunter B. Fraser
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Correspondence to Aaron E. Hirsh.

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Hirsh, A., Fraser, H. Rate of evolution and gene dispensability. Nature 421, 497–498 (2003). https://doi.org/10.1038/421497a

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