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Cost-free longevity in mice?

Studies of worms have revealed hundreds of proteins that, when mutated, extend lifespan. Can this work tell us anything about mammalian ageing? A look at the effects of one such protein on lab mice suggests that it can.

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Figure 1: Genetic dissection of the hormonal determinants of mammalian lifespan.


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Correspondence to Gordon J. Lithgow or Matthew S. Gill.

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Lithgow, G., Gill, M. Cost-free longevity in mice?. Nature 421, 125–126 (2003).

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