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Medicine

Tackling multiple sclerosis

New work in mice finds that certain anti-cholesterol drugs can reduce symptoms of disease in brain autoimmune disorders that are akin to human multiple sclerosis. There are also hints as to how the drugs might work.

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Figure 1: Brain disease.

References

  1. Youssef, S. et al. Nature 420, 78–84 (2002).

    Article  ADS  CAS  Google Scholar 

  2. Maron, D. J., Fazio, S. & Linton, M. F. Circulation 101, 207–213 (2000).

    CAS  Google Scholar 

  3. Stanislaus, R. Neurosci. Lett. 269, 71–74 (1999).

    Article  CAS  Google Scholar 

  4. Ludewig, B. et al. J. Immunol. 166, 3369–3376 (2001).

    Article  CAS  Google Scholar 

  5. Kwak, B., Mulhaupt, F., Myit, S. & Mach, F. Nature Med. 6, 1399–1402 (2000).

    Article  CAS  Google Scholar 

  6. Weitz-Schmidt, G. et al. Nature Med. 7, 687–692 (2001).

    Article  CAS  Google Scholar 

  7. Lanzavecchia, A. & Sallusto, F. Nature Immunol. 2, 487–492 (2001).

    Article  CAS  Google Scholar 

  8. Hohlfeld, R. Brain 120, 865–916 (1997).

    Article  Google Scholar 

  9. Steinman, L. J. Exp. Med. 194, F27–F30 (2001).

  10. Cruveilhier, J. Anatomie pathologique du corps humain (Baillière, Paris, 1841).

    Google Scholar 

Download references

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Correspondence to Hartmut Wekerle.

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Wekerle, H. Tackling multiple sclerosis. Nature 420, 39–40 (2002). https://doi.org/10.1038/420039a

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  • DOI: https://doi.org/10.1038/420039a

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