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Medicine

Tackling multiple sclerosis

New work in mice finds that certain anti-cholesterol drugs can reduce symptoms of disease in brain autoimmune disorders that are akin to human multiple sclerosis. There are also hints as to how the drugs might work.

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Figure 1: Brain disease.

References

  1. Youssef, S. et al. Nature 420, 78–84 (2002).

    ADS  CAS  Article  Google Scholar 

  2. Maron, D. J., Fazio, S. & Linton, M. F. Circulation 101, 207–213 (2000).

    CAS  Google Scholar 

  3. Stanislaus, R. Neurosci. Lett. 269, 71–74 (1999).

    CAS  Article  Google Scholar 

  4. Ludewig, B. et al. J. Immunol. 166, 3369–3376 (2001).

    CAS  Article  Google Scholar 

  5. Kwak, B., Mulhaupt, F., Myit, S. & Mach, F. Nature Med. 6, 1399–1402 (2000).

    CAS  Article  Google Scholar 

  6. Weitz-Schmidt, G. et al. Nature Med. 7, 687–692 (2001).

    CAS  Article  Google Scholar 

  7. Lanzavecchia, A. & Sallusto, F. Nature Immunol. 2, 487–492 (2001).

    CAS  Article  Google Scholar 

  8. Hohlfeld, R. Brain 120, 865–916 (1997).

    Article  Google Scholar 

  9. Steinman, L. J. Exp. Med. 194, F27–F30 (2001).

  10. Cruveilhier, J. Anatomie pathologique du corps humain (Baillière, Paris, 1841).

    Google Scholar 

Download references

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Correspondence to Hartmut Wekerle.

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Wekerle, H. Tackling multiple sclerosis. Nature 420, 39–40 (2002). https://doi.org/10.1038/420039a

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  • DOI: https://doi.org/10.1038/420039a

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