Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Molecular biology

RNA gets a grip on translation

These are interesting times for those who study RNA. The latest curious discovery is that some messenger RNAs have sequences that sense small molecules directly, so controlling translation of the RNA into protein.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: RNA as metabolite sensor and translation regulator.

References

  1. Winkler, W., Nahvi, A. & Breaker, R. R. Nature 419, 952–956 (2002); advance online publication, 16 October 2002 (doi:10.1038/nature01145).

    Article  ADS  CAS  Google Scholar 

  2. Nahvi, A. et al. Chem. Biol. 9, 1043–1049 (2002).

    Article  CAS  Google Scholar 

  3. Nou, X. & Kadner, R. J. Proc. Natl Acad. Sci. USA 97, 9170–9175 (2000).

    Article  Google Scholar 

  4. Miranda-Rios, J., Navarro, M. & Soberón, M. Proc. Natl Acad. Sci. USA 98, 9736–9741 (2001).

    Article  ADS  CAS  Google Scholar 

  5. Gelfand, M. S. et al. Trends Genet. 15, 439–442 (1999).

    Article  CAS  Google Scholar 

  6. Stormo, G. D. & Yongmei, J. Proc. Natl Acad. Sci. USA 98, 9465–9467 (2001).

    Article  ADS  CAS  Google Scholar 

  7. White, H. B. III J. Mol. Evol. 7, 101–104 (1976).

    Article  ADS  CAS  Google Scholar 

  8. Johansson, J. et al. Cell 110, 551–561 (2002).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jack W. Szostak.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Szostak, J. RNA gets a grip on translation. Nature 419, 890–891 (2002). https://doi.org/10.1038/419890a

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/419890a

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing