Like prisoners, condemned intracellular proteins are shackled with chains to await their fate. These chains are a signal that the proteins must be destroyed and are removed on protein degradation. New work shows how.
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Wilkinson, K. Unchaining the condemned. Nature 419, 351–353 (2002). https://doi.org/10.1038/419351a
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DOI: https://doi.org/10.1038/419351a
