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Developmental biology

Sharp peaks from shallow sources

Nature volume 419, pages 261–262 (2002)Cite this article

The use of mathematical modelling to formulate and test theories is still quite rare in biology. It has now been applied to show how a robust, sharp peak of signalling molecules can be formed in developing fruitfly embryos.

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Figure 1: Model for generating a sharp gradient of bone morphogenetic proteins (BMPs) in fruitfly embryos, according to Eldar et al.3.

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Authors and Affiliations

  1. the Department of Evolutionary Biology, Max-Planck-Institut für Entwicklungsbiologie, Spemannstrasse 37–39/IV, Tübingen, D-72076, Germany

    Hans Meinhardt

  2. the Institute for Developmental Biology, Universität zu Köln, Gyrhofstrasse 17, Köln, 50923, Germany

    Siegfried Roth

Authors
  1. Hans Meinhardt
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  2. Siegfried Roth
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Meinhardt, H., Roth, S. Sharp peaks from shallow sources. Nature 419, 261–262 (2002). https://doi.org/10.1038/419261a

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