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Stuck at first base

People with the genetic disease Peutz–Jeghers syndrome have many intestinal polyps — benign tissue outgrowths. These seldom become malignant, and the reason may lie in the properties of the affected gene.

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Figure 1: Development of intestinal cancer from intestinal polyps.
Figure 2: A different type of tumour suppressor?


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van der Weyden, L., Jonkers, J. & Bradley, A. Stuck at first base. Nature 419, 127–128 (2002).

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