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Cell motility

Braking WAVEs

A Correction to this article was published on 26 September 2002

When cells move, they alter their internal skeleton to push membrane out at the front and pull it in at the back. New work fills in some of the gaps in our knowledge of how this process is regulated.

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Figure 1: Regulation of actin polymerization, and hence cell movement, by the WASP and WAVE proteins.

References

  1. http://www.hopkinsmedicine.org/cellbio/devreotes/neutrophil.mov

  2. Ridley, A. J. Trends Cell Biol. 11, 471–477 (2001).

    Article  CAS  Google Scholar 

  3. Eden, S., Rohatgi, R., Podtelejnikov, A. V., Mann, M. & Kirschner, M. W. Nature 418, 790–793 (2002).

    Article  CAS  Google Scholar 

  4. Higgs, H. N. & Pollard, T. D. Annu. Rev. Biochem. 70, 649–676 (2001).

    Article  CAS  Google Scholar 

  5. Hahne, P., Sechi, A., Benesch, S. & Small, J. V. FEBS Lett. 492, 215–220 (2001).

    Article  CAS  Google Scholar 

  6. Nakagawa, H. et al. J. Cell Sci. 114, 1555–1565 (2001).

    CAS  PubMed  Google Scholar 

  7. Miki, H., Yamaguchi, H., Suetsugu, S. & Takenawa, T. Nature 408, 732–735 (2000).

    Article  CAS  Google Scholar 

  8. Fukuoka, M. et al. J. Cell Biol. 152, 471–482 (2001).

    Article  CAS  Google Scholar 

  9. Gruenheid, S. et al. Nature Cell Biol. 3, 856–859 (2001).

    Article  CAS  Google Scholar 

  10. Li, W., Fan, J. & Woodley, D. T. Oncogene 20, 6403–6417 (2001).

    Article  CAS  Google Scholar 

  11. Baumgartner, S. et al. J. Mol. Biol. 251, 41–49 (1995).

    Article  CAS  Google Scholar 

  12. Hummel, T., Leifker, K. & Klambt, C. Genes Dev. 14, 863–873 (2000).

    CAS  PubMed  PubMed Central  Google Scholar 

  13. Suzuki, T. et al. Genomics 63, 246–254 (2000).

    Article  CAS  Google Scholar 

  14. Stradal, T. et al. Curr. Biol. 11, 891–895 (2001).

    Article  CAS  Google Scholar 

Download references

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Correspondence to Anne J. Ridley.

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Cory, G., Ridley, A. Braking WAVEs. Nature 418, 732–733 (2002). https://doi.org/10.1038/418732a

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