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HIV

A tough viral nut to crack

HIV cannot multiply in certain human cells unless it expresses a protein called Vif, the function of which has finally been revealed. It seems that it overcomes a human protein that would otherwise block viral replication.

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Figure 1: How HIV-1 can overcome our cells' defences.

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Correspondence to Roger J. Pomerantz.

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Pomerantz, R. A tough viral nut to crack. Nature 418, 594–595 (2002). https://doi.org/10.1038/418594a

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