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Developmental biology

Decisions, decisions!

Nature volume 418, pages 282–283 (2002)Cite this article

Early embryo cells can develop either into specialized body cells or into precursors of eggs or sperm. It is not understood how this crucial decision is made in mammals, but new work brings us closer to the answer.

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Figure 1: Model for the development of primordial germ cells (PGCs) in mouse embryos, according to Saitou et al.2.

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  1. Department of Cell and Developmental Biology, Howard Hughes Medical Institute, Vanderbilt University Medical School, C-2310 Medical Center North, Nashville, 37232-2175, Tennessee, USA

    Brigid Hogan

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  1. Brigid Hogan
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Correspondence to Brigid Hogan.

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Hogan, B. Decisions, decisions!. Nature 418, 282–283 (2002). https://doi.org/10.1038/418282a

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