Many researchers have tried to increase the flux through metabolic pathways in cells by raising the supply of metabolic enzymes. Little attention has been paid to the demand side of the equation — until now.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Koebmann, B. J., Westerhoff, H. V., Snoep, J. L., Nilsson, D. & Jensen, P. R. J. Bacteriol. 184, 3909–3916 (2002).
Kacser, H. & Burns, J. A. Symp. Soc. Exp. Biol. 27, 65–104 (1973).
Niederberger, P., Prasad, R., Miozzari, G. & Kacser, H. Biochem. J. 287, 473–479 (1992).
Hofmeyr, J.-H & Cornish-Bowden, A. FEBS Lett. 467, 47–51 (2000).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Oliver, S. Demand management in cells. Nature 418, 33–34 (2002). https://doi.org/10.1038/418033a
Issue Date:
DOI: https://doi.org/10.1038/418033a
This article is cited by
-
Improvement of pyruvate production based on regulation of intracellular redox state in engineered Escherichia coli
Biotechnology and Bioprocess Engineering (2017)
-
Circadian mRNA expression: insights from modeling and transcriptomics
Cellular and Molecular Life Sciences (2016)
-
Thermodynamics—old laws in medicine and complex disease
Nature Biotechnology (2003)
