Most ion channels open and close — they are 'gated' — in response to cues in their environment. A crystal structure of a Ca2+-gated K+-ion channel provides insight into how gating works.
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References
Jiang, Y. et al. Nature 417, 515–522 (2002).
Jiang, Y. et al. Nature 417, 523–526 (2002).
Doyle, D. A. et al. Science 280, 69–77 (1998).
Zhou, Y., Morais-Cabral, J. H., Kaufman, A. & MacKinnon, R. Nature 414, 43–48 (2001).
Morais-Cabral, J. H., Zhou, Y. & MacKinnon, R. Nature 414, 37–42 (2001).
Jiang, Y., Pico, A., Cadene, M., Chait, B. T. & MacKinnon, R. Neuron 29, 593–601 (2001).
Schumacher, M. A., Rivard, A. F., Bachinger, H. P. & Adelman, J. P. Nature 410, 1120–1124 (2001).
Xia, X.-M et al. Nature 395, 503–507 (1998).
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Schumacher, M., Adelman, J. An open and shut case. Nature 417, 501–502 (2002). https://doi.org/10.1038/417501a
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DOI: https://doi.org/10.1038/417501a
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