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Developmental biology

Signalling polarity

Nature volume 417, pages 239–240 (2002)Cite this article

Cell signalling pathways triggered by Wnt proteins control gene expression and cell behaviour, especially during development. Work on frogs reveals another specific role for these proteins, and the signalling involved.

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Figure 1: Opposing signalling pathways, triggered by different members of the Wnt protein family, may help determine the polarity of Xenopus embryos.

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Authors and Affiliations

  1. the Howard Hughes Medical Institute and Department of Pharmacology, University of Washington School of Medicine, Seattle, 98195, Washington, USA

    Randall T. Moon & Kavita Shah

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  1. Randall T. Moon
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  2. Kavita Shah
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Moon, R., Shah, K. Signalling polarity. Nature 417, 239–240 (2002). https://doi.org/10.1038/417239a

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