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Interfering with bone remodelling

As they mature, bone-resorbing cells trigger the production of their own 'off-switch' — the interferon-β protein — to prevent the runaway bone loss that is seen in diseases such as osteoporosis.

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Figure 1: Balancing bone remodelling.

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Alliston, T., Derynck, R. Interfering with bone remodelling. Nature 416, 686–687 (2002). https://doi.org/10.1038/416686a

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