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Immunology

DNA drives autoimmunity

Nature volume 416, pages 595–597 (2002)Cite this article

In autoimmune diseases, a person's tissues are destroyed by their own immune system. IgG, a normal component of blood, provokes autoimmune responses when immune cells recognize it as a complex with DNA.

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Figure 1: Toll-like receptor proteins in immunity and autoimmunity.

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Authors and Affiliations

  1. Medical Genome Centre, John Curtin School of Medical Research, The Australian National University, Mills Road, PO Box 334, Canberra, ACT 2601, Australia

    Carola G. Vinuesa & Christopher C. Goodnow

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  1. Carola G. Vinuesa
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  2. Christopher C. Goodnow
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Vinuesa, C., Goodnow, C. DNA drives autoimmunity. Nature 416, 595–597 (2002). https://doi.org/10.1038/416595a

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