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Developmental biology

The plastic face

Nature volume 416, pages 493–494 (2002)Cite this article

In vertebrates, the face is formed in part by neural crest cells. It has been assumed that the developmental fate of these cells is inbuilt. New work, however, reveals a role for instructive signals from nearby cells.

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Figure 1: Shaping the face.

References

  1. Le Douarin, N. M. The Neural Crest (Cambridge Univ. Press, 1983).

  2. Noden, D. M. Dev. Biol. 96, 144–165 (1983).

    Article  CAS  Google Scholar 

  3. Trainor, P. A., Ariza-McNaughton, L. & Krumlauf, R. Science 295, 1288–1291 (2002).

    Article  ADS  CAS  Google Scholar 

  4. Couly, G., Creuzet, S., Bennaceur, S., Vincent, C. & Le Douarin, N. M. Development 129, 1061–1073 (2002).

    CAS  PubMed  Google Scholar 

  5. Gendron-Maguire, M., Mallo, M., Zhang, M. & Gridley, T. Cell 75, 1317–1331 (1993).

    Article  CAS  Google Scholar 

  6. Grammatopoulos, G. A., Bell, E., Toole, L., Lumsden, A. & Tucker, A. S. Development 127, 5355–5365 (2000).

    CAS  PubMed  Google Scholar 

  7. Pasqualetti, M., Ori, M., Nardi, I. & Rijli, F. M. Development 127, 5367–5378 (2000).

    CAS  PubMed  Google Scholar 

  8. Rijli, F. M. et al. Cell 75, 1333–1349 (1993).

    Article  CAS  Google Scholar 

  9. Irving, C. & Mason, I. Development 127, 177–186 (2000).

    CAS  PubMed  Google Scholar 

  10. Couly, G., Grapin-Botton, A., Coltey, P., Ruhin, B. & Le Douarin, N. M. Development 125, 3445–3459 (1998).

    CAS  PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, Illkirch Cedex, BP 163-67404, CU de Strasbourg, France

    Massimo Pasqualetti & Filippo M. Rijli

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  1. Massimo Pasqualetti
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  2. Filippo M. Rijli
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Correspondence to Filippo M. Rijli.

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Pasqualetti, M., Rijli, F. The plastic face. Nature 416, 493–494 (2002). https://doi.org/10.1038/416493a

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