In mammals, mother and father make an equal genetic, but an unequal 'epigenetic', contribution to offspring. Studies of humans and mice with no maternal epigenetic contribution reveal more about this asymmetry.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Judson, H., Hayward, B. E., Sheridan, E. & Bonthron, D. T. Nature 416, 539–542 (2002).
Bourc'his, D., Xu, G.-L, Lin, C.-S, Bollman, B. & Bestor, T. H. Science 294, 2536–2539 (2001).
Hata, H., Okano, M., Lei, H. & Li, E. Development (in the press).
Obata, Y. et al. Development 125, 1553–1560 (1998).
Reik, W. & Walter, J. Nature Genet. 27, 255–256 (2001).
Kato, Y. et al. Development 126, 1823–1832 (1999).
Aapola, U. et al. Genomics 65, 293–298 (2000).
Okano, M., Bell, D. W., Haber, D. A. & Li, E. Cell 99, 247–257 (1999).
Tamaru, H. & Selker, E. U. Nature 414, 277–283 (2001).
Surani, M. A. Nature 414, 122–128 (2001).
Nicholls, R. D. et al. J. Clin. Invest. 105, 423–418 (2000).
Mayer, W. et al. Nature 403, 501–502 (2000).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Surani, M. Immaculate misconception. Nature 416, 491–493 (2002). https://doi.org/10.1038/416491a
Issue Date:
DOI: https://doi.org/10.1038/416491a
This article is cited by
-
Cell Lines Derived from Human Parthenogenetic Embryos Can Display Aberrant Centriole Distribution and Altered Expression Levels of Mitotic Spindle Check-point Transcripts
Stem Cell Reviews and Reports (2009)
-
Demethylation of (Cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development
Cancer and Metastasis Reviews (2008)
-
Safeguarding ART
Nature Medicine (2002)
-
Cardiovascular and diabetes mortality determined by nutrition during parents' and grandparents' slow growth period
European Journal of Human Genetics (2002)