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Ready to unlearn

After rabbits learn to associate a tone with a small shock near the eye, they blink when they hear the tone. Learning requires activation of nerve fibres known as climbing fibres. Inhibition of these fibres leads to 'unlearning'.

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Figure 1: Brain circuitry involved in acquisition and extinction of pavlovian eye-blink responses, studied in rabbits.


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Correspondence to Shigeru Kitazawa.

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Kitazawa, S. Ready to unlearn. Nature 416, 271–273 (2002).

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