Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.


A cool ion channel

Researchers are getting warm in their search for the details of cold detection. The discovery of a cold-sensitive ion channel will help dissect how the nervous system encodes and decodes the temperature spectrum.

This is a preview of subscription content, access via your institution

Access options

Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. McKemy, D. D., Neuhausser, W. M. & Julius, D. Nature 416, 52–58 (2002); online 10 February 2002 (DOI 10.1038/nature719).

    ADS  CAS  Article  Google Scholar 

  2. Peier, A. et al. Cell online 11 February 2002 (DOI 10.1016/S0092867402006529).

  3. Caterina, M. J. et al. Nature 389, 816–824 (1997).

    ADS  CAS  Article  Google Scholar 

  4. Caterina, M. J. et al. Nature 398, 436–441 (1999).

    ADS  CAS  Article  Google Scholar 

  5. Julius, D. & Bausmam, A. I. Nature 413, 203–210 (2001).

    ADS  CAS  Article  Google Scholar 

  6. Askwith, C. C. et al. Proc. Natl Acad. Sci. USA 98, 6459–6463 (2001).

    ADS  CAS  Article  Google Scholar 

  7. Pierau, F. K., Torrey, P. & Carpenter, D. O. Brain Res. 73, 156–160 (1974).

    CAS  Article  Google Scholar 

  8. Carpenter, D. O. Fed. Proc. 40, 2808–2813 (1981).

    CAS  PubMed  Google Scholar 

  9. Viana, F., de la Peña, E. & Belmonte, C. Nature Neurosci. 5, 254–260 (2002); online 11 February 2002 (DOI 10.1038/nn809).

    CAS  Article  Google Scholar 

  10. Reid, G. & Flonta, M. L. Nature 413, 480 (2001).

    ADS  CAS  Article  Google Scholar 

  11. Hemsel, H. & Zotterman, Y. Acta Physiol. Scand. 24, 27–34 (1951).

    Article  Google Scholar 

  12. Clapham, D. E., Runnels, L. W. & Strubing, C. Nature Rev. Neurosci. 2, 387–396 (2001).

    CAS  Article  Google Scholar 

  13. Chen, C. C., Rainville, P. & Bushnell, M. C. Pain 68, 33–43 (1996).

    CAS  Article  Google Scholar 

  14. Tsavaler, L. et al. Cancer Res. 61, 3760–3769 (2001).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Charles S. Zuker.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Zuker, C. A cool ion channel. Nature 416, 27–28 (2002).

Download citation

  • Issue Date:

  • DOI:


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing