An enzyme involved in one aspect of DNA repair is now shown to have another function that improves the accuracy of repair. The new findings should help to improve therapies for HIV.
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APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling
Nature Communications Open Access 27 January 2021
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Jiricny, J. An APE that proofreads. Nature 415, 593–594 (2002). https://doi.org/10.1038/415593a
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DOI: https://doi.org/10.1038/415593a
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