Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Molecular motors

Stretching the lever-arm theory

Motor proteins are essential to life: without them, all cellular transport would grind to a halt. New results on the size of steps taken by one family of motors, the myosins, will fuel the debate about how they move.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Motor movement.

References

  1. Myosin Home Page; http://www.mrc-lmb.cam.ac.uk/myosin/myosin.html

  2. Cyranoski, D. Nature 408, 764–766 (2000).

    Article  ADS  CAS  Google Scholar 

  3. Geeves, M. A. & Holmes, K. C. Annu. Rev. Biochem. 68, 687–728 (1999).

    Article  CAS  Google Scholar 

  4. Tanaka, H. et al. Nature 415, 192–195 (2002).

    Article  ADS  CAS  Google Scholar 

  5. Nishikawa, S. et al. Biochem. Biophys. Res. Commun. (in the press).

  6. Rock, R. S. et al. Proc. Natl Acad. Sci. USA 98, 13655–13659 (2001).

    Article  ADS  CAS  Google Scholar 

  7. Viegel, C., Wang, F., Bartoo, M. L., Sellers, J. R. & Molloy, J. E. Nature Cell Biol. 10.1038/ncb732 (2001).

  8. Moore, J. R. et al. J. Cell Biol. 155, 625–635 (2001).

    Article  CAS  Google Scholar 

  9. Uyeda, T. Q. et al. Proc. Natl Acad. Sci. USA 93, 4459–4464 (1996).

    Article  ADS  CAS  Google Scholar 

  10. Anson, M. et al. EMBO J. 15, 6069–6074 (1996).

    Article  CAS  Google Scholar 

  11. Ruff, C., Furch, M., Brenner, B., Manstein, D. J. & Meyhöfer, E. Nature Struct. Biol. 8, 226–229 (2001).

    Article  CAS  Google Scholar 

  12. Walker, M. L. et al. Nature 405, 804–807 (2000).

    Article  ADS  CAS  Google Scholar 

  13. Wells, A. L. et al. Nature 401, 505–508 (1999).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Michael A. Geeves.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Geeves, M. Stretching the lever-arm theory. Nature 415, 129–131 (2002). https://doi.org/10.1038/415129a

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/415129a

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing