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An end to the protection racket

To modify a specific site on a molecule that has several similar sites, organic chemists have had to use cumbersome 'protecting groups'. New peptide catalysts with remarkable selectivities offer a protection-free alternative.

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Figure 1: Synthetic peptide catalyst in action.
Figure 2: Favouring one reaction over another.


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Correspondence to David Gani.

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Gani, D. An end to the protection racket. Nature 414, 703–705 (2001).

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