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Role of altered brain serotonin mechanisms in autism

Molecular Psychiatry volume 7, pages S16–S17 (2002)Cite this article

Autism is a developmental disorder defined by the presence of a triad of communication, social and stereo- typical behavioral characteristics with onset before 3 years of age. Autism may be a component feature of several genetic disorders, and underlying the remaining cases of autism are undoubtedly multiple etiologies. In spite of the fact that there are various etiologies for autistic behavior, the possibility of a common neuro- chemical mechanistic feature, shared by multiple causes of autism, cannot be excluded. It is upon this premise that functional neuroimaging of groups of autistic subjects of unknown etiology is compared to nonautistic control groups in search of common biological substrates.

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Authors and Affiliations

  1. Associate Professor of Pediatrics and Radiology, Wayne State University and Children's Hospital of Michigan,

    D C Chugani

  2. PET Center, Children's Hospital of Michigan, Detroit, MI, USA

    D C Chugani

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  1. D C Chugani
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Correspondence to D C Chugani.

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Chugani, D. Role of altered brain serotonin mechanisms in autism. Mol Psychiatry 7 (Suppl 2), S16–S17 (2002). https://doi.org/10.1038/sj.mp.4001167

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