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Major corrections are indicated for ‘Comparative proteome analysis of the hippocampus implicates chromosome 6q in schizophrenia’

Molecular Psychiatry volume 6, pages 10–12 (2001)Cite this article

SIR – We are writing to point out major corrections of Edgar et al1 which affect the conclusions of the authors. Edgar et al1 identify four proteins, based on partial protein sequence, isoelectric point, and molecular weight, which appear to be expressed at different amounts in schizophrenia brains vs normal brains, specifically in the hippocampus. The authors’ key conclusion regarding localization of the proteins which they identified is that three of the four localize to chromosome 6q, a result which they calculate to be significant at the P = 0.002 level.

We have disagreements with Edgar et al1 in three main areas:

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Authors and Affiliations

  1. Department of Psychiatry, Schizophrenia Genetics Research Program, The University of Chicago, Chicago, 60637, IL, USA

    A R Sanders & P V Gejman

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  1. A R Sanders
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  2. P V Gejman
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Correspondence to A R Sanders.

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Sanders, A., Gejman, P. Major corrections are indicated for ‘Comparative proteome analysis of the hippocampus implicates chromosome 6q in schizophrenia’. Mol Psychiatry 6, 10–12 (2001). https://doi.org/10.1038/sj.mp.4000802

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