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Knocking out the stress response

Abstract

Transgenic animals and knockout mice have been generated with defined defects in various components of the hypothalamic-pituitary-adrenal axis and the autonomic nervous system. These models provide valuable and novel insights into the development, crosstalk, organization, and functioning of the stress system.

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Correspondence to S R Bornstein.

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Bornstein, S., Böttner, A. & Chrousos, G. Knocking out the stress response. Mol Psychiatry 4, 403–407 (1999). https://doi.org/10.1038/sj.mp.4000602

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