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Does early morning versus late morning draw time influence apparent testosterone concentration in men aged ⩾45 years? Data from the Hypogonadism In Males study

International Journal of Impotence Research volume 20, pages 162–167 (2008)Cite this article

Abstract

The Hypogonadism In Males study estimated the prevalence of hypogonadism in men aged ⩾45 years. A sub-analysis of patients not receiving testosterone (T) therapy was conducted. Blood draw times were 0800–1000 and 1000–1200 hours. Total T (TT) was not influenced by draw time for any age group; however, significantly greater free T (FT) and bioavailable T (BAT) values were observed in the overall population for earlier draw times. Sex hormone-binding globulin (SHBG) values were significantly lower in men aged 45–64 years at the earlier draw time. In men aged ⩾75 years, no significant differences in TT, FT, BAT or SHBG were observed on the basis of draw time. Early morning draw time may not be critical for capturing TT concentrations in men ⩾45 years; however, when measuring FT or BAT, an early morning draw time may be preferable for men aged <75 years.

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Acknowledgements

Solvay Pharmaceuticals Inc. provided financial support for this study and editorial assistance in the preparation of this paper. Dr Guay has served on advisory boards for Auxilium, Oscient, Solvay, Cellegy, Procter & Gamble and Indevus. He has participated in speakers' bureaus for Auxilium, Oscient and Solvay and has been the recipient of research grants from Auxilium, Solvay and Cellegy. Dr Miller and Ms McWhirter are employees of Solvay Pharmaceuticals Inc.

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  1. Department of Endocrinology, Center for Sexual Function, Lahey Clinic, One Essex Center Drive, Peabody, MA, USA

    A Guay

  2. Solvay Pharamaceuticals Inc., Marietta, GA, USA

    M G Miller & C L McWhirter

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  1. A Guay
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  2. M G Miller
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  3. C L McWhirter
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Correspondence to A Guay.

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Guay, A., Miller, M. & McWhirter, C. Does early morning versus late morning draw time influence apparent testosterone concentration in men aged ⩾45 years? Data from the Hypogonadism In Males study. Int J Impot Res 20, 162–167 (2008). https://doi.org/10.1038/sj.ijir.3901580

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