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The prevalence of Peyronie's disease in diabetic patients with erectile dysfunction

International Journal of Impotence Research volume 19, pages 213–217 (2007)Cite this article

Abstract

We attempted in this study to investigate the prevalence of Peyronie's disease (PD) among diabetic patients with erectile dysfunction (ED). Two-hundred and six diabetic patients were further evaluated in this study. Forty-two (20.3%) patients had PD. There were significant associations between PD and risk factors of age, obesity and smoking. All patients with PD had also ED. Penile curvature was present in 82.1% of all patients with PD. Of the patients with PD, 25.4% had pain with or without erection. Significant associations between PD and ED and ED duration were detected. This study confirmed the high prevalence of PD among diabetic patients with ED. Further work is needed probing the mechanisms through which diabetes affects the pathogenesis of ED and PD.

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References

  1. Smith BH . Peyronie's disease. Am J Clin Pathol 1966; 45: 670–678.

    Article  CAS  Google Scholar 

  2. Sommer F, Schwarzer U, Wassmer G, Bloch W, Braun M, Klotz T et al. Epidemiology of Peyronie's disease. Int J Impot Res 2002; 14: 379–383.

    Article  CAS  Google Scholar 

  3. Schwarzer U, Sommer F, Klotz T, Braun M, Reifenrath B, Engelmann U . The prevalence of Peyronie's disease: results of a large survey. BJU Int 2001; 88: 727–730.

    Article  CAS  Google Scholar 

  4. Smith CJ, McMahon C, Shabsigh R . Peyronie's disease: the epidemiology, aetiology and clinical evaluation of deformity. BJU Int 2005; 95: 729–732.

    Article  Google Scholar 

  5. Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB . Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol 1994; 151: 54–61.

    Article  CAS  Google Scholar 

  6. Rendell MS, Rajfer J, Wicker PA, Smith MD . Sildenafil for treatment of erectile dysfunction in men with diabetes: a randomized controlled trial. Sildenafil Diabetes Study Group. JAMA 281; 421: 1999.

    Google Scholar 

  7. El-Sakka AI, Tayeb KA . Peyronie's disease in diabetic patients being screened for erectile dysfunction. J Urol 2005; 174: 1026–1030.

    Article  Google Scholar 

  8. Rosen RC, Cappelleri JC, Smith MD, Lipsky J, Pena BM . Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction. Int J Impot Res 1999; 11: 319–326.

    Article  CAS  Google Scholar 

  9. Mulhall JP . Expanding the paradigm for plaque development in Peyronie's disease. Int J Impot Res 2003; 15 (Suppl 5): S93–S102.

    Article  Google Scholar 

  10. Tefekli A, Kandirali E, Erol B, Tunc M, Kadioglu A . Peyronie's disease: a silent consequence of diabetes mellitus. Asian J Androl 2006; 8: 75–79.

    Article  CAS  Google Scholar 

  11. Chew KK, Stuckey BG, Earle CM, Dhaliwal SS, Keogh EJ . Penile fibrosis in intracavernosal prostaglandin E1 injection therapy for erectile dysfunction. Int J Impot Res 1997; 9: 225–229.

    Article  CAS  Google Scholar 

  12. Lopez JA, Jarow JP . Duplex ultrasound findings in men with Peyronie's disease. Urol Radiol 1991; 12: 199–202.

    Article  CAS  Google Scholar 

  13. Rhoden EL, Teloken C, Ting HY, Lucas ML, Teodosio da Ros C, Ary Vargas Souto C . Prevalence of Peyronie's disease in men over 50-y-old from Southern Brazil. Int J Impot Res 2001; 13: 291–293.

    Article  CAS  Google Scholar 

  14. La Pera G, Pescatori ES, Calabrese M, Boffini A, Colombo F, Andriani E et al. Peyronie's disease: prevalence and association with cigarette smoking. A multicenter population-based study in men aged 50–69 years. Eur Urol 2001; 40: 525–530.

    Article  CAS  Google Scholar 

  15. Levine LA, Coogan CL . Penile vascular assessment using color duplex sonography in men with Peyronie's disease. J Urol 1996; 155: 1270–1273.

    Article  CAS  Google Scholar 

  16. Usta MF, Bivalacqua TJ, Tokatli ZR, Rivera F, Gulkesen K, Sikka S et al. Stratification of penile vascular pathologies in patients with Peyronie's disease and in men with erectile dysfunction according to age: a comparative study. J Urol 2004; 172: 259–262.

    Article  Google Scholar 

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Author notes

  1. R Shamloul

    Present address: Department of Physiology, University of Saskatchewan, 107 Wiggins Road, Saskatoon, Saskatchwewan, Canada, S7N5E5

Authors and Affiliations

  1. Sexology and STD's Department, Andrology, Cairo University Hospital, Cairo, Egypt

    M Arafa & R Shamloul

  2. Dr Fakhry Hospital, El-Khobar, Saudi Arabia

    M Arafa, H Eid, A El-Badry & K Ezz-Eldine

  3. Radiology Department, Menofeya University, Sheebeen, Egypt

    H Eid

  4. Internal Medicine Department, Cairo University, Cairo, Egypt

    A El-Badry

  5. Urology Department, Menia University, Menya, Egypt

    K Ezz-Eldine

Authors
  1. M Arafa
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  2. H Eid
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  3. A El-Badry
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  4. K Ezz-Eldine
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  5. R Shamloul
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Correspondence to R Shamloul.

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Arafa, M., Eid, H., El-Badry, A. et al. The prevalence of Peyronie's disease in diabetic patients with erectile dysfunction. Int J Impot Res 19, 213–217 (2007). https://doi.org/10.1038/sj.ijir.3901518

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  • DOI: https://doi.org/10.1038/sj.ijir.3901518

Keywords

  • Peyronie
  • erectile dysfunction
  • prevalence

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