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Sex and the brain: the role of fMRI for assessment of sexual function and response


We briefly review the technique of functional brain imaging and its application in the assessment of the sexual response in men and women.

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  1. Kwong KK, Belliveau JW, Chesler DA, Chesler DA, Goldberg IE, Weisskoff RM et al. Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc Natl Acad Sci USA 1992; 89: 5675–5679.

    Article  CAS  Google Scholar 

  2. Ogawa S, Tank DW, Menon R, Ellermann JM, Kim SG, Merkle H et al. Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging. Proc Natl Acad Sci USA 1992; 89: 5951–5955.

    Article  CAS  Google Scholar 

  3. Stoleru S, Gregoire MC, Gerard D, Decety J, Zafarge E, Cinotti Z et al. Neuroanatomical correlates of visually evoked sexual arousal in human males. Arch Sex Behav 1999; 28: 1–21.

    Article  CAS  Google Scholar 

  4. Park K, Kang HK, Seo JJ, Kim HJ, Ryu SB, Jeong GW . Blood-oxygenation-level-dependent functional magnetic resonance imaging for evaluating cerebral regions of female sexual arousal response. Urology 2001; 57: 1189–1194.

    Article  CAS  Google Scholar 

  5. Karama S, Lecours AR, Leroux JM, Bourgouin P, Beaudoin G, Joubert S et al. Areas of brain activation in males and females during viewing of erotic film excerpts. Hum Brain Mapp 2002; 16: 1–13.

    Article  Google Scholar 

  6. Hamann S, Herman RA, Nolan CL, Wallen K . Men and women differ in amygdala response to visual sexual stimuli. Nat Neurosci 2004; 7: 411–416.

    Article  CAS  Google Scholar 

  7. Heekeren HR, Wartenburger I, Schmidt H, Schwintowski HP, Villringer A . An fMRI study of simple ethical decision-making. NeuroReport 2003; 14: 1215–1219.

    Article  Google Scholar 

  8. Moll J, de Oliveira-Souza R, Bramati IE, Grafman J . Functional networks in emotional moral and nonmoral social judgments. Neuroimage 2002; 16(3 Part 1): 696–703.

    Article  Google Scholar 

  9. Montorsi F, Perani D, Anchisi D, Salonia A, Scifo P, Rigoroli P et al. Brain activation patterns during video sexual stimulation following the administration of apomorphine: results of a placebo-controlled study. Eur Urol 2003; 43: 405–411.

    Article  CAS  Google Scholar 

  10. Komisaruk BR, Whipple B, Crawford A, Liu WC, Kalnin A, Mosier K . Brain activation during vaginocervical self-stimulation and orgasm in women with complete spinal cord injury: fMRI evidence of mediation by the vagus nerves. Brain Res 2004; 1024: 77–88.

    Article  CAS  Google Scholar 

  11. Ferretti A, Caulo M, Del Gratta C, Di Matteo R, Merla A, Montorsi F et al. Dynamics of male sexual arousal: distinct components of brain activation revealed by fMRI. Neuroimage 2005; 26: 1086–1096.

    Article  Google Scholar 

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Correspondence to C C Yang.

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Maravilla, K., Yang, C. Sex and the brain: the role of fMRI for assessment of sexual function and response. Int J Impot Res 19, 25–29 (2007).

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