Abstract
To assess the efficacy of vacuum constriction devices (VCD) following radical prostatectomy (RP) and determine whether early use of VCD facilitates early sexual activity and potentially earlier return of erectile function. This prospective study consisted of 109 patients who underwent nerve-sparing (NS) or non-nerve-sparing (NNS) RP between August 1999 and October 2001 and developed erectile dysfunction following surgery. The patients were randomized to VCD use daily for 9 months (Group 1, N=74) or observation without any erectogenic treatment (Group 2, N=35). Treatment efficacy was analyzed by responses to the Sexual Health Inventory of Men (SHIM) (abridged 5-item International Index of Erectile Function (IIEF-5)), which were stratified by the NS status. Patient outcome regarding compliance, change in penile length, return of natural erection, and ability for vaginal intercourse were also assessed. The mean patient age was 58.2 years, and the minimum follow-up was 9 months. Use of VCD began at an average of 3.9 weeks after RP. In Group 1, 80% (60/74) successfully used their VCD with a constriction ring for vaginal intercourse at a frequency of twice/week with an overall spousal satisfaction rate of 55% (33/60). In all, 19 of these 60 patients (32%) reported return of natural erections at 9 months, with 10/60 (17%) having erections sufficient for vaginal intercourse. The abridged IIEF-5 score significantly increased after VCD use in both the NS and NNS groups. After a mean use of 3 months, 14/74 (18%) discontinued treatment. In Group 2, 37% (13/35) of patients regained spontaneous erections at a minimum follow-up of 9 months after surgery. However, only four of these patients (29%) had erections sufficient for successful vaginal intercourse and rest of patients (71%) sought adjuvant treatment. Of the 60 successful users, 14 (23%) reported a decrease in penile length and circumference at 9 months (range, 4–8 months) compared to 12/14 (85%) among the nonresponders. However, in control group 22/35 reported decrease in penile length and circumference. Early use of VCD following RP facilitates early sexual intercourse, early patient/spousal sexual satisfaction, and potentially an earlier return of natural erections sufficient for vaginal penetration.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 8 print issues and online access
$259.00 per year
only $32.38 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Walsh PC, Marschke P, Ricker D, Burnett AL . Patient – reported urinary continence and sexual function after anatomic radical prostatectomy. Urology 2000; 55: 58–61.
McCullough AR . Management of erectile dysfunction following radical prostatectomy. Sexual Dysfunction Med Pfizer 2000; 2(1): 2–8.
Catalona WP, Basler JW . Return of erections and urinary continence following nerve-sparing radical retropubic prostatectomy. J Urol 1993; 150: 905–907.
Quinlan DM, Epstein JI, Carter BS, Walsh PC . Sexual function following radical prostatectomy: influence of preservation of neurovascular bundles. J Urol 1991; 145: 998–1002.
Zippe CD, Thukral M, Klein EA, Kedia S, Pasqualotto FF, Kedia A et al. Erectile dysfunction following radical prostatectomy in a pre-operative sexually active population. Poster Presentation at 95th Annual Meeting of AUA, Atlanta, GA, April 29–May 4, 2000.
Fraiman MC, Lepor H, McCullough AR . Changes in penile morphometrics in men with erectile dysfunction after nerve-sparing radical prostatectomy. Mol Urol 1999; 3: 109–115.
Zippe CD, Raina R, Thukral M, Lakin MM, Klein EA, Agarwal A . Management of erectile dysfunction following radical prostatectomy. Cur Urol Rep 2001; 2: 495–503.
Zippe CD, Jhaveri FM, Klein EA, Kedia S, Pasqualotto FF, Kedia A et al. Role of viagra after radical prostatectomy. Urology 2000; 55: 241–245.
Padma-Nathan H, McCullough AR, Giuliano F, Bicetre LK, Toler SM, Wohlhuter C et al. Postoperative nightly administration of sildenafil citrate significantly improves the return of normal spontaneous erectile function after bilateral nerve sparing radical prsotatectomy. J Urol 2003; 169: 375 (abstract #1402).
Cookson MS, Nadig PW . Long term results with vacuum constriction device. J Urol 1993; 149: 290–294.
Dutta TC, Eid JF . Vacuum constriction devices for erectile dysfunction: a long-term, prospective study of patients with mild, moderate, and severe dysfunction. Urology 1999; 54(5): 891–893.
Colombo F, Cogni M, Deiana G, Mastromarino G, Vecchio D, Patelli E et al. Vacuum therapy. Arch Ital Urol Nephrol Androl 1992; 64: 267–269.
Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J . The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile function. Urology 1997; 49: 822–830.
Rosen RC, Cappelleri JC, Smith MD, Lipsky J, Pena BM . Development and evaluation of an Abridged 5-Item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction. Int J Impot Res 1999; 11: 319–326.
Montorsi F, Guazzoni G, Strambi LF, Da Pozzo LF, Nava L, Barbieri L et al. Recovery of spontaneous erectile function after nerve-sparing radical retropubic prostatectomy with and without early intracavernous injections of alprostadil: results of a prospective, randomized trial. J Urol 1997; 158: 1408–1410.
Derouet H, Caspari D, Rohde V, Rommel G, Ziegler M . Treatment of erectile dysfunction with external vacuum devices. Andrologia 1999; 3: 89–94.
Levine LA, Dimitriou RJ . Vacuum constriction and external erection devices in erectile dysfunction. Urol Clin N Am 2001; 28: 335–341.
Sidi AA, Becher EF, Zhang G, Lewis JH . Patient acceptance of and satisfaction with an external negative pressure device for impotence. J Urol 1990; 144: 1154–1156.
Althof SE . When an erection alone is not enough: biopsychosocial obstacles to lovemaking. Int J Impot Res 2002; 14: S99–S104.
Rodriguez VL, Gonzalvo IA, Bono AA, Benejam GJ, Cuesta Presedo JM, Rioja Sanz LA . Erectile dysfunction after radical prostatectomy. etiopathology and treatment. Acta Urol Esp 1997; 21: 909–921.
Chen RN, Lakin MM, Montague DK, Ausmundson S . Prostaglandin E1 injection therapy for post-prostatectomy impotence: an outcome analysis. J Urol 1996; 155: 639.
Evans C . Complications of intracavernosal therapy for impotence. In: Carson C, Kirby R, Goldstein I (eds), Textbook of Erectile Dysfunction. Oxford: Isis Medical Media, 1999, pp. 365–370.
McAuley IW, Kim NN, Min K, Goldstein I, Traish AM . Intracavernosal sildenafil facilitates penile erection independent of the nitric oxide pathway. J Androl 2001; 22: 623–628.
Medina P, Segarra G, Vila JM, Domenech C, Martinez-Leon JB, Lluch S . Effects of sildenafil on human penile blood vessels. Urology 2000; 56: 539–543.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Raina, R., Agarwal, A., Ausmundson, S. et al. Early use of vacuum constriction device following radical prostatectomy facilitates early sexual activity and potentially earlier return of erectile function. Int J Impot Res 18, 77–81 (2006). https://doi.org/10.1038/sj.ijir.3901380
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/sj.ijir.3901380
Keywords
This article is cited by
-
Vacuum erection device for erectile function rehabilitation after radical prostatectomy: which is the correct schedule? Results from a systematic, scoping review
International Journal of Impotence Research (2023)
-
Vitamin D3 improved erectile function recovery by regulating autophagy and apoptosis in a rat model of cavernous nerve injury
International Journal of Impotence Research (2023)
-
Sexual health and treatment-related sexual dysfunction in sexual and gender minorities with prostate cancer
Nature Reviews Urology (2023)
-
Comparison of the efficacy of the early LI-SWT plus daily tadalafil with daily tadalafil only as penile rehabilitation for postprostatectomy erectile dysfunction
International Journal of Impotence Research (2023)
-
Response to Comment on ‘Comparison of the efficacy of the early LI-SWT plus daily tadalafil with daily tadalafil only as penile rehabilitation for postprostatectomy erectile dysfunction’
International Journal of Impotence Research (2023)