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Comparative study on evaluation methods for serum testosterone level for PADAM diagnosis

International Journal of Impotence Research volume 17, pages 259–263 (2005)Cite this article

Abstract

The International Society for the Study of the Aging Male (ISSAM) recommends that a diagnosis be based on a patient's total testosterone (TT), calculated free testosterone (cFT), or calculated bioavailable testosterone (cBT) for partial androgen deficiency of the aging male (PADAM). The purpose of this study was to confirm whether hypogonadism of patients with PADAM is related to symptoms and clarify which criteria of testosterone recommended by ISSAM is suitable for Japanese patients. A total of 90 patients with PADAM symptoms were included in this study. Endocrinologic profiles were reviewed as appropriate, and PADAM symptoms were judged by means of several questionnaires. Laboratory values and symptoms were compared between patients with and without hypogonadism. Even when any criterion of testosterone was used for diagnosis of hypogonadism, AMS (total and subscales), IIEF-5, or SDS scores of PADAM symptoms did not differ significantly between patients classified as having and not having hypogonadism. No other endocrinologic variables than testosterone differed significantly between them, either. PADAM symptoms are not related to testosterone level and it is still obscure whether ISSAM's criterion can be adopted for Japanese patients with PADAM. Other pathology needs to be addressed for evaluation and diagnosis of PADAM in Japan.

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Acknowledgements

We are very grateful to M Omune, M Oki, and S Tanabe of our laboratory for assistance in sample collection and for useful discussions.

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Authors and Affiliations

  1. Department of Urology, Osaka University Graduate School of Medicine, Suita, Japan

    A Tsujimura, K Matsumiya, Y Miyagawa, T Takao, K Fujita, S Takada & A Okuyama

  2. Department of Urology, Osaka Central Hospital, Osaka, Japan

    M Koga & M Takeyama

  3. Iwasa Clinic, Osaka, Japan

    A Iwasa

Authors
  1. A Tsujimura
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  2. K Matsumiya
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  3. Y Miyagawa
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  4. T Takao
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  5. K Fujita
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  6. S Takada
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  7. M Koga
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  8. A Iwasa
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  9. M Takeyama
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  10. A Okuyama
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Correspondence to A Tsujimura.

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Tsujimura, A., Matsumiya, K., Miyagawa, Y. et al. Comparative study on evaluation methods for serum testosterone level for PADAM diagnosis. Int J Impot Res 17, 259–263 (2005). https://doi.org/10.1038/sj.ijir.3901300

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  • DOI: https://doi.org/10.1038/sj.ijir.3901300

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