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Comparison of oxidative/antioxidative status of penile corpus cavernosum blood and peripheral venous blood

International Journal of Impotence Research volume 17, pages 19–22 (2005)Cite this article

Abstract

The aim of the study is to determine and to compare the oxidative and antioxidative status of penile corpus cavernosum and peripheral venous blood. A total of 28 adult healthy males were included in the study. Whole blood was simultaneously withdrawn from penile corpus cavernosum and the cubital vein and their plasma separated. Total antioxidant capacity (TAC), vitamin C, total protein, albumin, uric acid, bilirubin and total peroxide (TP) levels of both plasma samples were measured and compared. While TAC, total protein, albumin, bilirubin and uric acid levels were higher, vitamin C levels were lower in cavernosal blood than that of peripheral blood. On the other hand, TP level was found to be higher in penile blood samples than that of peripheral blood. We thought that the normal erectile process of the penile cavernosal body leads to increased production of oxidants as in the mechanism of ischaemia–reperfusion; however, the increase of TAC can prevent development of oxidative injury.

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Authors and Affiliations

  1. Department of Urology, Faculty of Medicine, Harran University, Sanliurfa, Turkey

    E Yeni, M Gulum, D Unal, A Verit & M Savas

  2. Department of Biochemistry, Faculty of Medicine, Harran University, Sanliurfa, Turkey

    S Selek & O Erel

Authors
  1. E Yeni
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  2. M Gulum
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  3. S Selek
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  4. O Erel
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  5. D Unal
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  6. A Verit
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  7. M Savas
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Correspondence to E Yeni.

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Yeni, E., Gulum, M., Selek, S. et al. Comparison of oxidative/antioxidative status of penile corpus cavernosum blood and peripheral venous blood. Int J Impot Res 17, 19–22 (2005). https://doi.org/10.1038/sj.ijir.3901262

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  • DOI: https://doi.org/10.1038/sj.ijir.3901262

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