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Does sexual dysfunction correlate with deterioration of somatic sensory system in diabetic women?

International Journal of Impotence Research volume 15, pages 198–202 (2003)Cite this article

Abstract

To evaluate genital and extragenital somatic sensory system in diabetic women using biothesiometry and investigate the relation with sexual dysfunction. A total of 30 diabetic women and 20 normal sexually active women as a control group were evaluated with a detailed medical and sexual history including Index of Female Sexual Function (IFSF) questionnaire. Somatic sensory system of all women enrolled to the study was assessed by biothesiometry and threshold sensory values of nine genital sites and 14 extragenital sites were analyzed. The IFSF score in diabetic women was 23.6 while it was 38.3 in the control group (<0.0005). For each genital as well as extragenital sites, the mean biothesiometric values were significantly higher in diabetics. The sensation of introitus vagina, labium minora and clitoris were found to be the most deteriorated genital sites in diabetic women. The difference between diabetic women with or without female sexual dysfunction (FSD) was not significant for biothesiometric values. Our data indicate that, somatic sensory system is affected by diabetes however sexual dysfunction does not always manifest.

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References

  1. Ellenberg M . Impotence in diabetes; the neurologic factor. Ann Intern Med 1971; 75: 213–219.

    Article  CAS  Google Scholar 

  2. Hosking DJ et al. Diabetic impotence: studies of nocturnal erection during REM sleep. BMJ 1979; 2: 1394–1396.

    Article  CAS  Google Scholar 

  3. Jevtich JV, Edson M, Jarman WD, Herrere HH . Vascular factor in erectile failure among diabetes. Urology 1982; 19: 163–168.

    Article  CAS  Google Scholar 

  4. Lehman PT, Jacobs JA . Etiology of diabetic impotence. J Urol 1983; 129: 291–294.

    Article  CAS  Google Scholar 

  5. Buvat J et al. Comparative investigations in 26 impotent and 26 non-impotent diabetic patients. J Urol 1985; 133: 34–38.

    Article  CAS  Google Scholar 

  6. Ryder REJ et al. Detailed investigation of the cause of impotence in 20 diabetic men. Pract Diabetes 1992; 9: 7–11.

    Article  Google Scholar 

  7. Goldstein I, Siroky MB . Impotence in diabetes mellitus. In: Krane RJ, Siroky MB, Goldstein I (eds). Male Sexual Dysfunction. Little, Brown: Boston, 1983.

    Google Scholar 

  8. Faerman I, Vıhan O, Binarola MA . Impotence and diabetes studies of androgenic function in diabetic impotent males. Diabetes 1972; 21: 23.

    Article  CAS  Google Scholar 

  9. Kinsey AC, Domeroy WB . Age and Sexual Outlet in Sexual Behavior in Human Male. W.B., Saunders: Philadelphia, 1948, p 218.

    Google Scholar 

  10. Kolodny RC, Kahn CB, Goldstein HH, Barnett DM . Sexual dysfunction in diabetic men. Diabetes 1974; 23: 306–309.

    Article  CAS  Google Scholar 

  11. Rubin A . Impotence and diabetes mellitus. J Am Med Assoc 1958; 165: 498.

    Article  Google Scholar 

  12. Wright AD, London DR, Holder G . Luteinizing release hormone tests in impotent diabetic males. Diabetes 1976; 25: 975.

    Article  CAS  Google Scholar 

  13. Kaplan SA et al. Safety and efficacy of sildenafil in postmenopausal women with sexual dysfunction. Urology 1999; 53: 481–486.

    Article  CAS  Google Scholar 

  14. Erol B et al. Sexual dysfunction in type II diabetic females: a comparative study. J Sex Marital Ther 2002; 28(Suppl): 55–62.

    Article  Google Scholar 

  15. Ralf S, Ulrich AM . Prevalence of sexual disorders in a selection-free diabetic population (JEVIN). Diab Res Clin Pract 1999; 44: 115–121.

    Article  Google Scholar 

  16. Brown MJ, Martin JR, Asbury AK . Painful diabetic neuropathy. Arch Neurol 1976; 33: 164–171.

    Article  CAS  Google Scholar 

  17. Padma-Nathan H, Goldstein I . Evaluation of impotent patient. Semin Urol 1986; 4: 230.

    Google Scholar 

  18. Vacek J, Lackman M . Bulbocavernous reflex in diabetics with erectile disorders, clinical and electromyographic study [Eng. abs]. Cas Lek Cesk 1977; 116: 1014.

    CAS  PubMed  Google Scholar 

  19. Vardi Y et al. Normative values for female genital sensation. Urology 2000; 56: 1035–1040.

    Article  CAS  Google Scholar 

  20. Zaslanky R, Yarnitsky D . Clinical applications of quantitative sensory testing. J Neur Sci 1998; 153: 215–238.

    Article  Google Scholar 

  21. Kadıoğlu A et al. The effects of diabetes on penile somatoafferent system. Arch Esp Urol 1994; 47: 100–103.

    PubMed  Google Scholar 

  22. Berman JR et al. Clinical evaluation of female sexual function; effects of age and estrogen status on subjective and physiologic sexual responses. Int J Impot Res 1999; 11(Suppl 1): 531–538.

    Google Scholar 

  23. Saenz De Tejeda I, Andry C, Blanco R . Ultrastructural studies of autonomic nerves within the corpus cavernosum of impotent diabetic patients. In: Virag H, Virag R (eds). Proceedings of the First World Meeting on Impotence, Paris, Les Editions Du Ceri, 1986, p 210.

  24. Marson L . Central nervous system neurons identified after injection of pseudorabies virus into the rat clitoris. Neurosci Lett 1995; 190: 41–44.

    Article  CAS  Google Scholar 

  25. Wagner G . Aspects of genital physiology and pathology. Semin Neurol 1992; 12: 87.

    Article  CAS  Google Scholar 

  26. Levin RJ . The mechanism of human female sexual arousal. Annu Rev Sex Res 1992; 3: 1.

    Article  Google Scholar 

  27. Levin RJ . The physiology of sexual function in women. Clin Obstet Gynecol 1980; 7: 213.

    CAS  Google Scholar 

  28. Schiavi RC, Segraves RT . The biology of sexual function. Psychiatr Clin North Am 1995; 18: 7.

    Article  CAS  Google Scholar 

  29. Levin RJ . VIP, vagina, clitoral and periurethral glans: an update on female genital arousal. Exp Clin Endocrinol 1991; 98: 61.

    Article  CAS  Google Scholar 

  30. Ottesen B . Vasoactive intestinal polypeptide as a neurotransmitter in the female genital tract. Am J Obstet Gynecol 1983; 147: 203.

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Urology, Section of Andrology, Medical Faculty of Istanbul, University of Istanbul, Capa-Istanbul, Turkey

    B Erol, A Tefekli, O Sanli, O Ziylan, A Armagan, M Kendirci, D Eryasar & A Kadioglu

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  1. B Erol
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  2. A Tefekli
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  3. O Sanli
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  4. O Ziylan
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  5. A Armagan
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  6. M Kendirci
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  7. D Eryasar
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  8. A Kadioglu
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Correspondence to A Kadioglu.

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Erol, B., Tefekli, A., Sanli, O. et al. Does sexual dysfunction correlate with deterioration of somatic sensory system in diabetic women?. Int J Impot Res 15, 198–202 (2003). https://doi.org/10.1038/sj.ijir.3900998

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  • DOI: https://doi.org/10.1038/sj.ijir.3900998

Keywords

  • diabetes mellitus
  • somatic sensory system
  • biothesiometry and sexual dysfunction

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