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The nucleotide sequence of Saccharomyces cerevisiae chromosome VII

Nature volume 387, pages 81–84 (1997)Cite this article

The complete nucleotide sequence of Saccharomyces cerevisiae chromosome VII has 572 predicted open reading frames (ORFs), of which 341 are new. No correlation was found between G+C content and gene density along the chromosome, and their variations are random. Of the ORFs, 17% show high similarity to human proteins. Almost half of the ORFs could be classified in functional categories, and there is a slight increase in the number of transcription (7.0 %) and translation (5.2 %) factors when compared with the complete S. cerevisiae genome. Accurate verification procedures demonstrate that there are less than two errors per 10,000 base pairs in the published sequence.

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Author information

Author notes

  1. B. Fartmann

    Present address: MWG-BIOTECH GmbH, Anzinger Strasse 7, D-85560, Ebersberg, Germany

  2. M. García-Gonzalez

    Present address: Centro de Biotecnología, Camagüey, Cuba

  3. B. Kramer

    Present address: Abteilung Klinische Biochemie, Zentrum Innere Medizin, Georg-August-Universität, Robert-Koch-Strasse 40, D-37075, Göttingen, Germany

Authors and Affiliations

  1. Unité de Biochimie Physiologique, Université Catholique de Louvain, Place Croix-du-Sud 2/20, B-1348, Louvain-la-Neuve, Belgium

    H. Tettelin, S. Del Bino, P. de Wergifosse, A. Goffeau, B. Purnelle, E. Talla & L. Van Dyck

  2. Dipartimento di Genetica e di Biologia dei Microrganismi, Università di Milano, via Celoria 26, I-20133, Milano, Italy

    M. L. Agostoni Carbone, P. Melchioretto, L. Panzeri & P. Plevani

  3. Martinsrieder Institut für Protein Sequenzen, Max-Planck-Institut für Biochemie, Am Klopferspitz 18a, D-82152, Martinsried, Germany

    K. Albermann, J. Hani, K. Heumann, H. W. Mewes, A. Zollner & K. Kleine

  4. Institut für Biologie IV, Mikrobiologie, Worringerweg, RWTH-Aachen, D-52056, Germany

    M. Albers, U. Backes, A. Coblenz, M. Hansen, H. Leuther, R. Neu, B. Schäfer, A. Schreer, K. Wolf & M. Zimmermann

  5. Departamento de Microbiología II and Centro de Secuenciación de DNA de la UCM, Faculdad de Farmacia, Universidad Complutense, E-28040, Madrid, Spain

    J. Arroyo, M. García-Gonzalez, M. I. García-Sáez, C. Nombela & M. Sánchez-Perez

  6. Laboratorio de Genetica Molecular, Instituto Gulbenkian de Ciencia, Ap 14, E-2781, Oeiras Codex, Portugal

    T. Barreiros, P. Guerreiro & C. Rodrigues-Pousada

  7. Microbiology Group, International Center for Genetic Engineering and Biotechnology, Padriciano 99, I-34012, Trieste, Italy

    I. Bertani, C. V. Bruschi, M. Coglievina, D. Delneri, R. Klima & P. Zaccaria

  8. The Biotechnology Center for Animal and Plant Health, The Queens University of Belfast, Newforge Lane, Belfast, BT9 5PX, UK

    A. J. Bjourson, A. D. K. McReynolds & L. F. Wright

  9. Genotype GmbH, Angelhofweg 39, D-69259, Wilhelmsfeld, Germany

    M. Brückner, S. Müller-Auer, M. Rieger & M. Schäfer

  10. Dipartimento di Chimica biologica, Università di Padova, via Trieste 75, I-35121, Padova, Italy

    G. Carignani, M. L. Clemente & F. Feroli

  11. Dipartimento di Biologia, Università di Roma ‘Tor Vergata’, via della Ricerca Scientifica, I-00133, Roma, Italy

    L. Castagnoli, O. Minenkova & S. Paoluzi

  12. Departamento de Biologia Celular y Molecular, Facultad de Ciencias, Universidad de La Coruna, Campus de La Zapateira s/n, La Coruna, Spain

    E. Cerdan, E. Rodriguez-Belmonte & A. M. Rodriguez-Torres

  13. Centre de Génétique Moléculaire, CNRS, Laboratoire Associé à l’Université Pierre et Marie Curie, F-91198, Gif-sur-Yvette Cedex, France

    E. Coissac, E. Maillier & P. Netter

  14. Katholieke Universiteit Leuven, Laboratory of Gene Technology, Willem de Croylaan 42, B-3001, Leuven, Belgium

    E. Defoor, J. Robben, P. Verhasselt, M. Voet & G. Volckaert

  15. Department for Applied Virology, Deutsches Krebsforschungszentrum, D-69120, Heidelberg, Germany

    H. Delius, U. Hebling & B. Hofmann

  16. Unité de Génétique Moléculaire des levures (URA 1149 of CNRS and UPR 927 of University P.M. Curie, Paris), Department of Biotechnologies, Institut Pasteur, 25 rue du Dr. Roux, F-75724, Paris, Cedex 15, France

    B. Dujon & A. Thierry

  17. Unité de Microbiologie, Faculté Universitaire des Sciences Agronomiques de Gembloux, Avenue Maréchal Juin 6, B-5030, Gembloux, Belgium

    P. Durand, F. Hilger, D. Portetelle & M. Vandenbol

  18. Institut für Mikrobiologie der Johann Wolfgang Goethe-Universität Frankfurt/Main, Marie-Curie Strasse 9, D-60439, Frankfurt, Germany

    K. D. Entian, P. Kötter & M. Rose

  19. Departamento de Bioquímica, Facultad de Medicina de la U.A.M., Instituto de Investigaciones Biomédicas del C.S.I.C.y, E-28029, Madrid, Spain

    P. Eraso, V. Escribano, M. J. Mazón & F. Portillo

  20. Dipartimento di Biologia Cellulare e dello Sviluppo, Università di Roma La Sapienza, P. le Aldo Moro 5, I-00185, Roma, Italy

    L. Fabiani, L. Frontali, A. Marconi, C. Mazzoni, T. Rinaldi & M. Saliola

  21. Institut für Molekulare Genetik, Georg-August-Universität, Grisebachstr. 8, D-37077, Göttingen, Germany

    B. Fartmann, B. Kramer & W. Kramer

  22. Laboratoire de Microbiologie et Génétique URA 1481, Université Louis Pasteur/CNRS, Institut de Botanique, rue Goethe 28, F-67083, Strasbourg Cedex, France

    M. Feuermann, S. Potier & J. L. Souciet

  23. Microsynth GmbH, Schützenstrasse 15, CH-9436, Balgach, Switzerland

    K. Hernandez, T. Schmidheini, N. Weber & P. Wipfli

  24. Department of Biochemistry and Applied Molecular Biology, UMIST, PO Box 88, Sackville Street, Manchester, M60 1QD, UK

    K. J. Indge, C. M. James & S. G. Oliver

  25. Institut de Biochimie Cellulaire, CNRS, rue Camille Saint-Saèns 1, F-33077, Bordeaux Cedex, France

    G. Lauquin

  26. Yeast Genetics, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, OX3 9DU, UK

    E. J. Louis

  27. Dipartimento di Biochimica e Fisiologia Generali, Università di Milano, via Celoria 26, I-20133, Milano, Italy

    E. Martegani & M. Vanoni

  28. Institute of Microbiology, Wroclaw University, Przybyszewskiego 63, P-51148, Wroclaw, Poland

    A. Nawrocki & J. Skala

  29. Genome Sequencing Center and Department of Genetics, Washington University School of Medicine, St Louis, Missouri, 63110, USA

    L. Riles

  30. Dipartimento di Agrobiologia e Agrochimica, Università della Tuscia, via S. Camillo de Lellis, I-01100, Viterbo, Italy

    M. Ruzzi

  31. AGON GmbH, Glienicker Weg 185, D-12489, Berlin, Germany

    M. Scharfe, R. Wambutt, E. Wedler & H. Wedler

  32. Institute for Molecular Plant Sciences, Leiden University, Wassenaarseweg 64, NL-2333, AL Leiden, The Netherlands

    H. Y. Steensma & Q. J. M. van der Aart

  33. Department of Microbiology and Enzymology, Delft University of Technology, Julianalaan 67, NL-2628, BC Delft, The Netherlands

    H. Y. Steensma

  34. Department of Biological Sciences, University of Durham, South Road, Durham, DH1 3LE, UK

    M. D. Watson

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  2. M. L. Agostoni Carbone
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Corresponding author

Correspondence to A. Goffeau.

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Tettelin, H., Agostoni Carbone, M.L., Albermann, K. et al. The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. Nature 387 (Suppl 6632), 81–84 (1997). https://doi.org/10.1038/387s081

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