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Evidence for a clade of nematodes, arthropods and other moulting animals

Nature volume 387, pages 489–493 (1997)Cite this article

Abstract

The arthropods constitute the most diverse animal group, but, despite their rich fossil record and a century of study, their phylogenetic relationships remain unclear1. Taxa previously proposed to be sister groups to the arthropods include Annelida, Onychophora, Tardigrada and others, but hypotheses of phylogenetic relationships have been conflicting2,3. For example, onychophorans, like arthropods, moult periodically, have an arthropod arrangement of haemocoel1,4, and have been related to arthropods in morphological and mitochondrial DNA sequence analyses4,5. Like annelids, they possess segmental nephridia and muscles that are a combination of smooth and obliquely striated fibres6. Our phylogenetic analysis of 18S ribosomal DNA sequences indicates a close relationship between arthropods, nematodes and all other moulting phyla. The results suggest that ecdysis (moulting) arose once and support the idea of a new clade, Ecdysozoa, containing moulting animals: arthropods, tardigrades, onychophorans, nematodes, nematomorphs, kinor-hynchs and priapulids. No support is found for a clade of segmented animals, the Articulata, uniting annelids with arthropods. The hypothesis that nematodes are related to arthropods has important implications for developmental genetic studies using as model systems the nematode Caenorhabditis elegans and the arthropod Drosophila melanogaster, which are generally held to be phylogenetically distant from each other.

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Authors and Affiliations

  1. Molecular Biology Institute and MCD Biology, University of California, Los Angeles, California, 90095, USA

    Anna Marie A. Aguinaldo, Lawrence S. Linford, Maria C. Rivera & James A. Lake

  2. Department of Biological Sciences, University of Arkansas, Fayetteville, Arkansas, 72701, USA

    James M. Turbeville

  3. Department of Biological Sciences, Duquesne University, Pittsburgh, Pennsylvania, 15282

    James R. Garey

  4. Department of Biology, University of South Florida, Tampa, Florida, 33620, USA

    James R. Garey

  5. Department of Biology and Indiana Molecular Biology Institute, Indiana University, Bloomington, Indiana, 47405, USA

    Rudolf A. Raff

Authors
  1. Anna Marie A. Aguinaldo
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  2. James M. Turbeville
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  3. Lawrence S. Linford
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  4. Maria C. Rivera
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  5. James R. Garey
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  6. Rudolf A. Raff
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  7. James A. Lake
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Aguinaldo, A., Turbeville, J., Linford, L. et al. Evidence for a clade of nematodes, arthropods and other moulting animals. Nature 387, 489–493 (1997). https://doi.org/10.1038/387489a0

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