Consolidation in human motor memory

Abstract

LEARNING a motor skill sets in motion neural processes that continue to evolve after practice has ended, a phenomenon known as consolidation1–4. Here we present psychophysical evidence for this, and show that consolidation of a motor skill was disrupted when a second motor task was learned immediately after the first. There was no disruption if four hours elapsed between learning the two motor skills, with consolidation occuring gradually over this period. Previous studies in humans and other primates have found this time-dependent disruption of consolidation only in explicit memory tasks5–12, which rely on brain structures in the medial temporal lobe9,13,14. Our results indicate that motor memories, which do not depend on the medial temporal lobe8,15, can be transformed by a similar process of consolidation. By extending the phenomenon of consolidation to motor memory, our results indicate that distinct neural systems share similar characteristics when encoding and storing new information.

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References

  1. 1

    Bailey, C. H. & Kandel, E. R. in The Cognitive Neurosciences (ed. Gazzaniga, M.) 19–36 (MIT Press, Cambridge, MA, 1995).

  2. 2

    Karni, A. & Sagi, D. Nature 365, 250–252 (1993).

  3. 3

    Tully, T., Preat, T., Boynton, S. C. & Del Vecchio, M. Cell 79, 35 (1994).

  4. 4

    Weingartner, H. & Parker, E. (eds) Memory Consolidation: Psychobiology of Cognition (L. Erlbaum, Hillsdale, 1984).

  5. 5

    Muller, G. & Pilzecker, A. Z. F. Psychol. 1, 1–228 (1900).

  6. 6

    Skaggs, E. Psychol. Monogr. 34, (1925).

  7. 7

    Sisson, D. E. J. exp. Psychol. 25, 228–233 (1939).

  8. 8

    Milner, B. Neuropsychologia 3, 317–338 (1965).

  9. 9

    Squire, L. R. & Alvarez, P. Curr. Opin. Neurobiol. 5, 169–177 (1995).

  10. 10

    Zola-Morgan, S. & Squire, L. R. Science 250, 288–290 (1990).

  11. 11

    McGeoch, J. & Irion, A. Am. J. Psychol. 43, 579–592 (1931).

  12. 12

    Squire, L. R., Slater, P. & Chace, P. Science 187, 77–79 (1975).

  13. 13

    Malamut, B. L. Saunders, R. C. & Mishkin, M. Behavl Neurosci. 98, 759–769 (1984).

  14. 14

    Zola-Morgan, S. & Squire, L. R. Behavl Neurosci. 99, 22–34 (1985).

  15. 15

    Corkin, S. Neuropsychologia 6, 255–265 (1969).

  16. 16

    Shadmehr, R. & Mussa-lvaldi, F. A. J. Neurosci. 14, 3208–3224 (1994).

  17. 17

    McGeoch, J. & Irion, A. Psychology of Human Learning 2nd edn, 299–467 (Longmans Breen, New York, 1952).

  18. 18

    Lewis, D., Smith, N. & McAllister, D. J. exp. Psychol. 44, 247–260 (1952).

  19. 19

    Shea, J. & Titzer, R. J. Mot. Behav. 25, 264–274 (1993).

  20. 20

    Alvarez, P. & Squire, L. R. Proc. natn. Acad. Sci. U.S.A. 91, 7041–7045 (1994).

  21. 21

    McClelland, J. L., McNaughton, B. L. & O'Reilly, R. C. Psychol. Rev. 102, 419–457 (1995).

  22. 22

    Mishkin, M., Malamut, B. & Bachevalier, J. Neurobiology of Learning and Memory (eds Lynch, G., McGaugh, J. L. & Weinberger, N. M.) 65–77 (Guilford, London, 1984).

  23. 23

    Kim, J. J., Clark, R. E. & Thompson, R. F. Behavl Neurosci. 109, 195–203 (1995).

  24. 24

    Fujii, S., Saito, K., Miyakawa, H., Ito, K. & Kato, H. Brain Res. 555, 112–122 (1991).

  25. 25

    Bailey, C. H. & Chen, M. Science 220, 91–93 (1983).

  26. 26

    Castro-Alamancos, M. A., Donoghue, J. P. & Connors, B. W. J. Neurosci. 15, 5324–5333 (1995).

  27. 27

    Kimura, A., Caria, M. A., Melis, F. & Asanuma, H. Neuroreport 5, 2372–2376 (1994).

  28. 28

    Ito, M. Can. J. neurol. Sci. 20, Suppl. 3, 70–74 (1993).

  29. 29

    Seeds, N. W., Williams, B. L. & Bickford, P. C. Science 270, 1992–1994 (1995).

  30. 30

    Faye, I. thesis, MIT (1986).

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Brashers-Krug, T., Shadmehr, R. & Bizzi, E. Consolidation in human motor memory. Nature 382, 252–255 (1996). https://doi.org/10.1038/382252a0

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