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Controlling chaos in the brain

Abstract

In a spontaneously bursting neuronal network in vitro, chaos can be demonstrated by the presence of unstable fixed-point behaviour. Chaos control techniques can increase the periodicity of such neuronal population bursting behaviour. Periodic pacing is also effective in entraining such systems, although in a qualitatively different fashion. Using a strategy of anticontrol such systems can be made less periodic. These techniques may be applicable to in vivo epileptic foci.

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Schiff, S., Jerger, K., Duong, D. et al. Controlling chaos in the brain. Nature 370, 615–620 (1994). https://doi.org/10.1038/370615a0

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