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Induction of germ cell formation by oskar

Nature volume 358, pages 387–392 (1992)Cite this article

Abstract

The oskar gene directs germ plasm assembly and controls the number of germ cell precursors formed at the posterior pole of the Drosophila embryo. Mislocalization of oskar RNA to the anterior pole leads to induction of germ cells at the anterior. Of the eight genes necessary for germ cell formation at the posterior, only three, oskar, vasa and tudor, are essential at an ectopic site.

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Author information

Author notes

  1. Anne Ephrussi

    Present address: European Molecular Biology Laboratory, Meyerhofstrasse 1, D-6900, Heidelberg, Germany

Affiliations

  1. Whitehead Institute for Biomedical Research, Department of Biology, Massachusetts Institute of Technology, Howard Hughes Medical Institute, 9 Cambridge Center, Cambridge, Massachusetts, 02142, USA

    Anne Ephrussi & Ruth Lehmann

Authors
  1. Anne Ephrussi
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  2. Ruth Lehmann
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Ephrussi, A., Lehmann, R. Induction of germ cell formation by oskar. Nature 358, 387–392 (1992). https://doi.org/10.1038/358387a0

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  • DOI: https://doi.org/10.1038/358387a0

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