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The C. elegans genome sequencing project: a beginning

Abstract

The long-term goal of this project is the elucidation of the complete sequence of the Caenorhabditis elegans genome. During the first year methods have been developed and a strategy implemented that is amenable to large-scale sequencing. The three cosmids sequenced in this initial phase are surprisingly rich in genes, many of which have mammalian homologues.

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Sulston, J., Du, Z., Thomas, K. et al. The C. elegans genome sequencing project: a beginning. Nature 356, 37–41 (1992). https://doi.org/10.1038/356037a0

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