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Minisatellite repeat coding as a digital approach to DNA typing

Nature volume 354, pages 204209 (21 November 1991) | Download Citation

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Abstract

Most DNA typing systems used in forensic and legal medicine assay allelic length variation at tandem repetitive DNA regions such as minisatellites. A simple alternative approach that displays patterns of variant repeat units along minisatellite alleles is described here. This produces DNA profiles as extraordinarily variable digital sequences appropriate for forensic investigations, including computer databasing, and for analysing allele diversity and the role of recombination in minisatellite instability.

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Affiliations

  1. Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH, UK

    • Alec J. Jeffreys
    • , Annette MacLeod
    • , Keiji Tamaki
    • , David L. Neil
    •  & Darren G. Monckton

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https://doi.org/10.1038/354204a0

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