This month marks a year since the launch of Nature Reviews Molecular Cell Biology — a year in which we hope you've found much to stimulate, inform and entertain you. To celebrate, we are offering free online access to the journal throughout October, as well as free access for three months to the two new additions to the Nature Reviews family — Nature Reviews Cancer and Nature Reviews Immunology.

October 2001 marks another significant anniversary, as discussed by Michael Scheid and James Woodgett on page 760. It is ten years since the discovery of protein kinase B (PKB) — alias AKT — was reported, during which time much has been learned about how it acts and is regulated. Evidence is now emerging, however, that some of the functions originally attributed to PKB/AKT may, in fact, be carried out by related kinases.

It's also almost ten years since CDK5 was identified as a member of the family of cyclin-dependent kinases, which are mainly involved in regulating the cell cycle. A decade later, it is clear that CDK5 is neither cyclin dependent nor is it involved in regulation of the cell cycle. Instead, as Rani Dhavan and Li-Huei Tsai discuss on page 749, its activity has been linked to various processes, from regulation of the cytoskeleton to axon guidance.

What does the next year hold for Nature Reviews Molecular Cell Biology? The format and content of the journal have proved very popular, but in response to feedback from our readers we've made several small changes. Full URLs will now be supplied in the Links boxes of our Highlights, Reviews and Perspectives, and we've also added the relevant URL for the web site featured in our 'web watch' column. Finally, we have introduced a new column — 'structure watch' — to the Highlights section, which will describe the functional implications of recent structural studies.