The study of how cells communicate impinges on all aspects of biology, from development to disease. At first glance it's a horrendously complicated business, but some simple themes are emerging.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
The First 3D Model of the Full-Length KIT Cytoplasmic Domain Reveals a New Look for an Old Receptor
Scientific Reports Open Access 25 March 2020
-
An ultrasensitive fiveplex activity assay for cellular kinases
Scientific Reports Open Access 19 December 2019
-
Manatee invariants reveal functional pathways in signaling networks
BMC Systems Biology Open Access 28 July 2017
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Schlessinger, J. Cell 103, 211–225 (2000).
Hunter, T. Phil. Trans. R. Soc. Lond. B. 353, 583–605 (1998).
Cohen, P. Trends Biochem. Sci. 25, 596–601 (2000).
Schlaepfer, D. D. & Hunter, T. Trends Cell Biol. 8, 151–157 (1998).
Daniel, J. M. & Reynolds, A. B. Bioessays 19, 883–891 (1997).
Massague, J. & Chen, Y. G. Genes Dev. 14, 627–644 (2000).
Pawson, T. & Scott, J. D. Science 278, 2075–2080 (1997).
Shields, J. M. et al. Trends Cell Biol. 10, 147–154 (2000).
Kornberg, R. D. Trends Cell Biol. 9, M46–M49 (1999).
Christophe, D. et al. Cell Signal. 12, 337–341 (2000).
Pawson, T. Nature 373, 573–580 (1995).
Whitmarsh, A. J. & Davis, R. J. Trends Biochem. Sci. 23, 481–485 (1998).
Plowman, G. D. et al. Proc. Natl Acad. Sci. USA 96, 13603–13610 (1999).
Datta, S. R. et al. Genes Dev. 13, 2905–2927 (1999).
Fruman, D. A. et al. Annu. Rev. Biochem. 67, 481–507 (1998).
Marshall, C. J. Cell 80, 179–185 (1995).
International Human Genome Sequencing Consortium. Nature 409, 860–921 (2001).
Venter, J. C. et al. Science 291, 1304–1351 (2001).
Walhout, A. J. M. & Vidal, M. Nature Rev. Mol. Cell Biol. 2, 55–62 (2001).
Oliver, S. G. et al. Trends Biotechnol. 16, 373–378 (1998).
Schulze, A. & Downward, J. J. Cell Sci. 113, 4151–4156 (2000).
Endy, D. & Brent, R. Nature 409, 391–395 (2001).
Hanahan, D. & Weinberg, R. A. Cell 100, 57–70 (2000).
Withers, D. J. & White, M. Endocrinology 141, 1917–1921 (2000).
Mauro, M. J. & Druker, B. J. Curr. Opin. Oncol. 13, 3–7 (2001).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Downward, J. The ins and outs of signalling. Nature 411, 759–762 (2001). https://doi.org/10.1038/35081138
Issue Date:
DOI: https://doi.org/10.1038/35081138
This article is cited by
-
Development and validation of multiple machine learning algorithms for the classification of G-protein-coupled receptors using molecular evolution model-based feature extraction strategy
Amino Acids (2021)
-
STIM1, STIM2, and PDI Participate in Cellular Fate Decisions in Low Energy Availability Induced by 3-NP in Male Rats
Neurotoxicity Research (2021)
-
The First 3D Model of the Full-Length KIT Cytoplasmic Domain Reveals a New Look for an Old Receptor
Scientific Reports (2020)
-
An ultrasensitive fiveplex activity assay for cellular kinases
Scientific Reports (2019)
-
Manatee invariants reveal functional pathways in signaling networks
BMC Systems Biology (2017)
