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Human genetics

Tackling common disease

Crohn's disease is characterized by inflammation and destruction of the bowel. Identification of defective variants of a gene that predispose people to the disease is an encouraging development.

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References

  1. Hugot, J.-P et al. Nature 411, 599–603 (2001).

    Article  ADS  CAS  Google Scholar 

  2. Ogura, Y. et al. Nature 411, 603–606 (2001).

    Article  ADS  CAS  Google Scholar 

  3. Hugot, J. et al. Nature 379, 772–773 (1996).

    Article  Google Scholar 

  4. Ogura, Y. et al. J. Biol. Chem. 276, 4812–4818 (2001).

    Article  CAS  Google Scholar 

  5. Fiocchi, C. Gastroenterology 115, 182–205 (1998).

    Article  CAS  Google Scholar 

  6. Schreiber, S., Nikolaus, S. & Hampe, J. Gut 42, 477–484 (1998).

    Article  CAS  Google Scholar 

  7. Brown, P. Nature 410, 1018–1020 (2001).

    Article  ADS  CAS  Google Scholar 

  8. Mahida, Y. R. & Johal, S. Clin. Exp. Immunol. 123, 347–349 (2001).

    Article  CAS  Google Scholar 

  9. Cho, J. Curr. Gastroenterol. Rep. 2, 434–439 (2000).

    Article  CAS  Google Scholar 

  10. Wahl, C., Liptay, S., Adler, G. & Schmid, R. M. J. Clin. Invest. 101, 1163–1174 (1998).

    Article  CAS  Google Scholar 

Download references

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Correspondence to John A. Todd.

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Todd, J. Tackling common disease. Nature 411, 537–539 (2001). https://doi.org/10.1038/35079223

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