The RIKEN Mouse Gene Encyclopaedia Project, a systematic approach to determining the full coding potential of the mouse genome, involves collection and sequencing of full-length complementary DNAs and physical mapping of the corresponding genes to the mouse genome. We organized an international functional annotation meeting (FANTOM) to annotate the first 21,076 cDNAs to be analysed in this project. Here we describe the first RIKEN clone collection, which is one of the largest described for any organism. Analysis of these cDNAs extends known gene families and identifies new ones.
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We thank the following (in alphabetical order) for discussion, encouragement and technical assistance: R. Abagyan, T. Akimura, K. Arakawa, M. Boguski, L. Corbani, T. A. Dragani, J. T. Eppig, S. Fujimori, G. Grillo, T. Haga, T. Hanagaki, S. Hanaoka, S. Hatta, N. Hayatsu, K. Hiramoto, T. Hiraoka, T. Hirozane, Y. Hodoyama, F. Hori, T. Hubbard, R. Hynes, K. Ikeda, K. Ikeo, C. Imamura, K. Imotani, S. Inoue, H. Kato, N. Kikuchi, Y. Kojima, A. Konagaya, M. Kouda, S. Koya, M. Kubota, S. Kumagai, C. Kurihara, M. Kusakabe, F. Licciulli, S. Liuni, L. Maltais, T. Matsuyama, L. McKenzie, A. Miyazaki, K. Mori, M. Muramatsu, M. Nakamura, K. Nomura, N. Nukina, K. Numata, R. Numazaki, M. Ohno, Y. Okuma, H. Ono, C. Owa, Y. Ozawa, G. Pertea, S. Ramachandran, E. M. Rubin, N. Saga, H. Saitou, H. Sakai, C. Sakai, A. Sakurai, H. Sano, D. Sasaki, L. Sato, C. Schneider, J. Schug, T. Shiraki, M. B. Soares, Y. Sogabe, C. Stoeckert, H. Sugawara, R. Sultana, H. Suzuki, M. Tagami, A. Tagawa, F. Takahashi, S. Takaku-Akahira, M. Takeuchi, T. Tanaka, Y. Tateno, Y. Tejima, J. Todd, A. Tomaru, S. Tonegawa, T. Toya, A. Wada, L. Wagner, A. Watahiki, T. Yamamura, T. Yamashita, T. Yao, A. Yasunishi, T. Yokota, S. Yokoyama, A. Yoshiki and K. Yotsutani. We also thank N. Kazuta, Y. Sigemoto, H. Torigoe and T. Washida for secretarial assistance. This study has been mainly supported by a grant for the RIKEN Genome Exploration Research Project and CREST (Core Research for Evolutional Science and Technology) to Y.H. Further support came from ACT-JST (Research and Development for Applying Advanced Computational Science and Technology) of Japan Science and Technology Corporation (JST) to Y.H. and H.M., and the Science and Technology Agency of the Japanese Government to Y.H. and Y.O. (All funds from the Science Technology Agency of the Japanese Government.) This work was also supported by a Grant-in-Aid for Scientific Research on Priority Areas and Human Genome Program, from the Ministry of Education, Science and Culture, and by a Grant-in-Aid for a Second Term Comprehensive 10-Year Strategy for Cancer Control from the Ministry of Health and Welfare to Y.H. Authors’ contributions: J. Kawai and Y. Okazaki contributed as organizers in phase II team and FANTOM, respectively. A. Shinagawa and H. Bono contributed as managers in sequence data production system and computing system, respectively. J. Quackenbush, P. Carninci, M. J. Brownstein, D. A. Hume, C. Schönbach, H. Suzuki and C. Weitz acted as senior managers of the annotation project.
DDBJ accsession number and MGI ID for RIKEN ID