The molecular mechanisms underlying the link between obesity and diabetes have been elusive. A new protein, christened 'resistin', can now be added to the panoply of factors that may be involved.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Steppan, C. M. et al. Nature 409, 307–312 (2001).
Kahn, B. B. & Flier, J. S. J. Clin. Invest. 106 , 473–481 (2000).
Boden, G. Proc. Assoc. Am. Physicians 111, 241– 248 (1999).
Hotamisligil, G. S., Peraldi, P. & Spiegelman, B. M. Curr. Opin. Endocrinol. Diab. 3, 16–23 (1996).
Friedman, J. M. & Halaas, J. L. Nature 395, 763–770 (1998).
Ahima, R. S. & Flier, J. S. Annu. Rev. Physiol. 62, 413–437 (2000).
Shimomura, I., Hammer, R. E., Ikemoto, S., Brown, M. S. & Goldstein, J. L. Nature 401, 73–76 (1999).
Considine, R. V. et al. New Engl. J. Med. 334, 292– 295 (1995).
Olefsky, J. M. J. Clin. Invest. 106, 467–472 (2000).
Lehmann, J. M. et al. J. Biol. Chem. 270, 12953– 12956 (1995).
Tontonoz, P. et al. Genes Dev. 8, 1224– 1234 (1994).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Flier, J. The missing link with obesity?. Nature 409, 292–293 (2001). https://doi.org/10.1038/35053251
Issue Date:
DOI: https://doi.org/10.1038/35053251