Trials in mice of a possible vaccine for Alzheimer's disease show that it reduces the behavioural defects and the brain damage seen in the disease. As promising as these results are, a human vaccine remains a long way off.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Bornemann, K. D. & Staufenbiel, M. Ann. NY Acad. Sci. 908, 260–266 ( 2000).
van Leuven, F. Prog. Neurobiol. 61, 305–312 (2000).
Schenk, D. et al. Nature 400, 173–177 (1999).
Janus, C. et al. Nature 408, 979–982 (2000).
Morgan, D. et al. Nature 408, 982–985 (2000).
Chen, G. et al. Nature 408, 975–979 (2000).
Games, D. et al. Nature 373, 523–527 (1995).
Holcomb, L. et al. Nature Med. 4, 97– 100 (1998).
Hsiao, K. et al. Science 274, 99–102 (1996).
Wischik, C. M., Edwards, P. C. & Harrington, C. R. Neurobiology of Alzheimer's Disease (eds Dawbard, D. & Allen, S. J.) 89–148 (BIOS Scientific, Oxford, 1995).
Lim, G. P. et al. J. Neurosci. 20, 5709– 5714 (2000).
Li, Y. M. et al. Nature 405, 689–694 (2000).
Vassar, R. et al. Science 286, 735–741 (1999).
Chapman, P. F. et al. Nature Neurosci. 2, 271– 276 (1999).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Chapman, P. Model behaviour. Nature 408, 915–916 (2000). https://doi.org/10.1038/35050179
Issue Date:
DOI: https://doi.org/10.1038/35050179
This article is cited by
-
New developments in animal models of Alzheimer’s disease
Current Neurology and Neuroscience Reports (2001)
