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Bone versus immune system

A molecule on activated T cells triggers bone loss by switching on bone-resorbing cells. Fortunately, it seems that this mechanism is kept in check by another molecule, secreted by the T cells.

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Figure 1: The interface between the immune system and bones.


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Correspondence to Joseph R. Arron or Yongwon Choi.

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Arron, J., Choi, Y. Bone versus immune system. Nature 408, 535–536 (2000).

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