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Surfing the p53 network

The p53 tumour-suppressor gene integrates numerous signals that control cell life and death. As when a highly connected node in the Internet breaks down, the disruption of p53 has severe consequences.

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Figure 1
Figure 2: Viral oncogenes and the p53 network.
Figure 3: The p53 network.

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Correspondence to Bert Vogelstein, David Lane or Arnold J. Levine.

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Vogelstein, B., Lane, D. & Levine, A. Surfing the p53 network. Nature 408, 307–310 (2000). https://doi.org/10.1038/35042675

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