Abstract
Among the herpesviruses1, KSHV (Kaposi's-sarcoma-associated herpesvirus) is the human prototype of the rhadinovirus genus2. Rhadinoviruses (or γ2-herpesviruses) are found in several animal species, including New and Old World monkeys, but not in the great apes3,4,5. Here we describe the detection and sequencing of a polymerase gene fragment from three new rhadinoviruses discovered in chimpanzees and in a gorilla, which are more closely related to KSHV than to any other virus of this genus described so far. Our results indicate that the great apes from central Africa could provide a reservoir of new γ2-herpesviruses that are potentially transmissible to humans.
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References
- 1.
Roizmann, B. et al. Arch. Virol. 123, 425– 449 (1992).
- 2.
Chang, Y. et al. Science 266, 1865–1869 (1994).
- 3.
Greensill, J. et al. J. Virol. 74, 1572– 1577 (2000).
- 4.
Desrosiers, R. C. et al. J. Virol. 71, 9764– 9769 (1997).
- 5.
Rose, T. M. et al. J. Virol. 71, 4138– 4144 (1997).
- 6.
Corbet, S. et al. J. Virol. 74, 529–534 (2000).
- 7.
Chatlynne, L. G. et al. Blood 92, 53–58 (1998).
- 8.
Hahn, B. H. et al. Science 287, 607–614 (2000).
- 9.
Heneine, W. et al. Nature Med. 4, 403– 407 (1998).
- 10.
Gao, F. et al. Nature 397, 436–441 (1999).
- 11.
Mahieux, R. et al. J. Virol. 72, 10316– 10322 (1998).
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Affiliations
*Unité d'Oncologie Virale, Département du SIDA et des Rétrovirus, Institut Pasteur, 25–28 rue du Dr Roux, 75724 Paris Cedex 15, France
- Vincent Lacoste
- , Philippe Mauclre
- & Antoine Gessain
†Centre Pasteur du Cameroun, BP 1274, Yaoundé, Cameroon
- Philippe Mauclre
‡Centre International de Recherches Médicales, Franceville, Gabon
- Guy Dubreuil
- & Marie-Claude Georges-Courbot
§International Zoo Veterinary group , Keighley, West Yorkshire BD21 1AG, UK
- John Lewis
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Correspondence to Antoine Gessain.
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