Abstract
Among the herpesviruses1, KSHV (Kaposi's-sarcoma-associated herpesvirus) is the human prototype of the rhadinovirus genus2. Rhadinoviruses (or γ2-herpesviruses) are found in several animal species, including New and Old World monkeys, but not in the great apes3,4,5. Here we describe the detection and sequencing of a polymerase gene fragment from three new rhadinoviruses discovered in chimpanzees and in a gorilla, which are more closely related to KSHV than to any other virus of this genus described so far. Our results indicate that the great apes from central Africa could provide a reservoir of new γ2-herpesviruses that are potentially transmissible to humans.
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References
Roizmann, B. et al. Arch. Virol. 123, 425– 449 (1992).
Chang, Y. et al. Science 266, 1865–1869 (1994).
Greensill, J. et al. J. Virol. 74, 1572– 1577 (2000).
Desrosiers, R. C. et al. J. Virol. 71, 9764– 9769 (1997).
Rose, T. M. et al. J. Virol. 71, 4138– 4144 (1997).
Corbet, S. et al. J. Virol. 74, 529–534 (2000).
Chatlynne, L. G. et al. Blood 92, 53–58 (1998).
Hahn, B. H. et al. Science 287, 607–614 (2000).
Heneine, W. et al. Nature Med. 4, 403– 407 (1998).
Gao, F. et al. Nature 397, 436–441 (1999).
Mahieux, R. et al. J. Virol. 72, 10316– 10322 (1998).
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Lacoste, V., Mauclre, P., Dubreuil, G. et al. KSHV-like herpesviruses in chimps and gorillas . Nature 407, 151–152 (2000). https://doi.org/10.1038/35025145
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DOI: https://doi.org/10.1038/35025145
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